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HOXD10 Antibody

CAT: 0223-56-534Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-534Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
NCBI Gene ID
3236
Swiss Prot
P28358
Accession Number
P28358
Host
Rabbit
Reactivity
Mouse, Zebrafish
Immunogen
This HOXD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human HOXD10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HOXD10
NCBI Official Name
Homeobox protein Hox-D10
NCBI Organism
Homo sapiens
Background Reference 01
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 02
Reddy, S.D., et al. Cancer Res. 68 (20) :8195-8200 (2008)
Background Reference 03
Gurnett, C.A., et al. Clin. Orthop. Relat. Res. 462, 27-31 (2007) :
Background Reference 04
Zhao, X., et al. Am. J. Hum. Genet. 80 (2) :361-371 (2007)
Other Product Names
Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E, HOXD10, HOX4D, HOX4E
Tested Applications
WB
Protein ID
143811403
Physical Properties
Liquid

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