Products for Research Use Only

CTNND2 Antibody

CAT: 0223-56-497Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-497Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.
NCBI Gene ID
1501
Swiss Prot
Q9UQB3
Accession Number
Q9UQB3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CTNND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of human CTNND2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
133 kDa
Fragment
Rabbit Ig
Symbol
CTNND2
NCBI Official Name
Catenin delta-2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Zhang, J., et al. Exp. Cell Res. 316 (6) :1070-1081 (2010)
Background Reference 03
Yang, I., et al. Mol. Cells 29 (3) :233-237 (2010)
Background Reference 04
Stenzel, N., et al. J. Cell. Sci. 122 (PT 18), 3374-3384 (2009) :
Other Product Names
Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP
Tested Applications
WB, IHC-P
Protein ID
84028193
Physical Properties
Liquid