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TCF7L2 Antibody

CAT: 0223-56-412Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-412Size:400 µL
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Background
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
NCBI Gene ID
6934
Swiss Prot
Q9NQB0
Accession Number
Q9NQB0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TCF7L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human TCF7L2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
TCF7L2
NCBI Official Name
Transcription factor 7-like 2
NCBI Organism
Homo sapiens
Background Reference 01
Hansson, O., et al. Curr. Diab. Rep. 10 (6) :444-451 (2010)
Background Reference 02
Heni, M., et al. Diabetes (2010) In press :
Background Reference 03
Potapov, V.A., et al. Genetika 46 (8) :1123-1131 (2010)
Background Reference 04
Kucharska-Newton, A.M., et al.Obes 2010 (2010) :
Other Product Names
Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, TCF-4, hTCF-4, TCF7L2, TCF4
Tested Applications
WB
Protein ID
29337146
Physical Properties
Liquid

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