Products for Research Use Only
RegisterLogin

CHRNA10 Antibody

CAT: 0223-56-266Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-56-266Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
NCBI Gene ID
57053
Swiss Prot
Q9GZZ6
Accession Number
Q9GZZ6
Host
Rabbit
Reactivity
Human
Immunogen
This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
CHRNA10
NCBI Official Name
Neuronal acetylcholine receptor subunit alpha-10
NCBI Organism
Homo sapiens
Background Reference 01
Saccone, N.L., et al. Genes Brain Behav. 9 (7) :741-750 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Rigbi, A., et al. Pharmacogenomics J. (2010) In press :
Background Reference 04
Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)
Other Product Names
Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10, CHRNA10, NACHRA10
Tested Applications
WB, IHC-P
Protein ID
14916526
Physical Properties
Liquid

Related Products

CatalogName
31-131CHRNA1 Antibody
28-215CHRNA1 Antibody
28-216CHRNA1 Antibody
56-130CHRNA2 Antibody
31-101CHRNA3 Antibody
15-362CHRNA6 Antibody
28-285CHRNA7 Antibody
23-605CHRNA6 Antibody
42-389CHRNA5 Antibody
31-093CHRNA7 Antibody

Alternative Products

CatalogName
MBS9506604-01CHRNA10 Antibody

Popular Products