CHRNA1 Antibody

• Background:

  The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.

• NCBI Gene ID:

  1134

• Swiss Prot:

  P02708-2

• Accession Number:

  NP_000070

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRNA1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRNA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Applications Notes:

  CHRNA1 antibody can be used for detection of CHRNA1 by ELISA at 1:312500. CHRNA1 antibody can be used for detection of CHRNA1 by western blot at 1.8 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CHRNA1

• NCBI Official Name:

  Cholinergic receptor, nicotinic, alpha 1 (muscle)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Webster, R., et al., (2004) Neurology 62 (7), 1090-1096.

• Other Product Names:

  CHRNA1, ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS

• Tested Applications:

  ELISA, WB

• Protein ID:

  4557457

• Physical Properties:

  Liquid