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PRDX4 Antibody

CAT: 0223-56-229Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-229Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
NCBI Gene ID
10549
Swiss Prot
Q13162
Accession Number
Q13162
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PRDX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human PRDX4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
PRDX4
NCBI Official Name
Peroxiredoxin-4
NCBI Organism
Homo sapiens
Background Reference 01
Jamaluddin, M., et al. J. Virol. 84 (18) :9533-9545 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Edvardsen, H., et al. Pharmacogenomics J. (2010) In press :
Background Reference 04
Wang, H.Q., et al. FEBS Lett. 583 (9) :1511-1515 (2009)
Other Product Names
Peroxiredoxin-4, Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372, PRDX4
Tested Applications
WB, IHC-P
Protein ID
3024727
Physical Properties
Liquid

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