PRDX4 Antibody

• Background :

  The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.

• NCBI Gene ID :

  10549

• Swiss Prot :

  Q13162

• Accession Number :

  Q13162

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This PRDX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human PRDX4.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  31 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  PRDX4

• NCBI Official Name :

  Peroxiredoxin-4

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Jamaluddin, M., et al. J. Virol. 84 (18) :9533-9545 (2010)

• Background Reference 02 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 03 :

  Edvardsen, H., et al. Pharmacogenomics J. (2010) In press :

• Background Reference 04 :

  Wang, H.Q., et al. FEBS Lett. 583 (9) :1511-1515 (2009)

• Other Product Names :

  Peroxiredoxin-4, Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372, PRDX4

• Tested Applications :

  WB, IHC-P

• Protein ID :

  3024727

• Physical Properties :

  Liquid