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MET Antibody

CAT: 0223-56-218Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-218Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4233
Swiss Prot
P08581
Accession Number
P08581
Host
Rabbit
Reactivity
Human
Immunogen
This ZNF593 antibody is generated from rabbits immunized with a His fusion protein from human MET.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
156 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MET
NCBI Official Name
Hepatocyte growth factor receptor
NCBI Organism
Homo sapiens
Background Reference 01
Song, J., et al. Arch. Pathol. Lab. Med. 134 (11) :1702-1705 (2010)
Background Reference 02
Thanseem, I., et al. Neurosci. Res. 68 (2) :137-141 (2010)
Background Reference 03
Holgren, C., et al. Oncogene 29 (38) :5241-5253 (2010)
Background Reference 04
Sugiura, T., et al. Clin. Immunol. 136 (3) :387-399 (2010)
Other Product Names
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met, MET
Tested Applications
WB
Protein ID
251757497
Physical Properties
Liquid

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