SH2D4A Antibody

• Background :

  SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

• NCBI Gene ID :

  63898

• Swiss Prot :

  Q9H788

• Accession Number :

  Q9H788

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SH2D4A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  53 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  SH2D4A

• NCBI Official Name :

  SH2 domain-containing protein 4A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Li, T., et al. BMB Rep 42 (8) :516-522 (2009)

• Background Reference 03 :

  Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

• Background Reference 04 :

  Lapinski, P.E., et al. J. Immunol. 181 (3) :2019-2027 (2008)

• Other Product Names :

  SH2 domain-containing protein 4A, Protein SH (2) A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A

• Tested Applications :

  WB, IHC-P

• Protein ID :

  74725117

• Physical Properties :

  Liquid