SH2D4A Antibody

• Background:

  SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

• NCBI Gene ID:

  63898

• Swiss Prot:

  Q9H788

• Accession Number:

  Q9H788

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SH2D4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SH2D4A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SH2D4A

• NCBI Official Name:

  SH2 domain-containing protein 4A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Li, T., et al. BMB Rep 42 (8) :516-522 (2009)

• Background Reference 03:

  Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

• Background Reference 04:

  Lapinski, P.E., et al. J. Immunol. 181 (3) :2019-2027 (2008)

• Other Product Names:

  SH2 domain-containing protein 4A, Protein SH (2) A, Protein phosphatase 1 regulatory subunit 38, SH2D4A, PPP1R38, SH2A

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74725117

• Physical Properties:

  Liquid