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S100A1 Antibody

CAT: 0223-56-036Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-036Size:400 µL
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Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
NCBI Gene ID
6271
Swiss Prot
P23297
Accession Number
P23297
Host
Rabbit
Reactivity
Human
Immunogen
This S100A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-75 amino acids from the C-terminal region of human S100A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
11 kDa
Fragment
Rabbit Ig
Symbol
S100A1
NCBI Official Name
Protein S100-A1
NCBI Organism
Homo sapiens
Background Reference 01
Marlatt, N.M., et al. Protein Expr. Purif. 73 (1) :58-64 (2010)
Background Reference 02
Van Dieck, J., et al. FEBS Lett. 584 (15) :3269-3274 (2010)
Background Reference 03
Sviatoha, V., et al. Melanoma Res. 20 (2) :118-125 (2010)
Background Reference 04
DeRycke, M.S., et al. Am. J. Clin. Pathol. 132 (6) :846-856 (2009)
Other Product Names
Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100A1, S100A
Tested Applications
WB, IHC-P
Protein ID
134136
Physical Properties
Liquid

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