Neuropilin-2 Antibody

• Background:

  This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF) . This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  8828

• Swiss Prot:

  O60462

• Accession Number:

  O60462

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Neuropilin-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the C-terminal region of human Neuropilin-2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  105 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NRP2

• NCBI Official Name:

  Neuropilin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rey-Gallardo, A., et al. Glycobiology 20 (9) :1139-1146 (2010)

• Background Reference 02:

  Geretti, E., et al. Mol. Cancer Res. 8 (8) :1063-1073 (2010)

• Background Reference 03:

  Guo-ping, W., et al. Ann Plast Surg 65 (1) :80-84 (2010)

• Background Reference 04:

  Nasarre, C., et al. Cell Adh Migr 3 (4) :383-389 (2009)

• Other Product Names:

  Neuropilin-2, Vascular endothelial cell growth factor 165 receptor 2, NRP2, VEGF165R2

• Tested Applications:

  WB

• Physical Properties:

  Liquid