DPP3 Antibody

• Background :

  This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.

• NCBI Gene ID :

  10072

• Swiss Prot :

  Q9NY33

• Accession Number :

  Q9NY33

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This DPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the C-terminal region of human DPP3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  83 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  DPP3

• NCBI Official Name :

  Dipeptidyl peptidase 3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Shukla, A.A., et al. FEBS J. 277 (8) :1861-1875 (2010)

• Background Reference 02 :

  Salopek-Sondi, B., et al. Biol. Chem. 389 (2) :163-167 (2008)

• Background Reference 03 :

  Gevaert, K., et al. Proteomics 5 (14) :3589-3599 (2005)

• Background Reference 04 :

  Abramic, M., et al. Int. J. Biochem. Cell Biol. 36 (3) :434-446 (2004)

• Other Product Names :

  Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III, Enkephalinase B, DPP3

• Tested Applications :

  WB, IHC-P, IF, Flow

• Protein ID :

  20532389

• Physical Properties :

  Liquid