DPP3 Antibody

• Background:

  This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.

• NCBI Gene ID:

  10072

• Swiss Prot:

  Q9NY33

• Accession Number:

  Q9NY33

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the C-terminal region of human DPP3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  83 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DPP3

• NCBI Official Name:

  Dipeptidyl peptidase 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shukla, A.A., et al. FEBS J. 277 (8) :1861-1875 (2010)

• Background Reference 02:

  Salopek-Sondi, B., et al. Biol. Chem. 389 (2) :163-167 (2008)

• Background Reference 03:

  Gevaert, K., et al. Proteomics 5 (14) :3589-3599 (2005)

• Background Reference 04:

  Abramic, M., et al. Int. J. Biochem. Cell Biol. 36 (3) :434-446 (2004)

• Other Product Names:

  Dipeptidyl peptidase 3, Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, Dipeptidyl peptidase III, DPP III, Enkephalinase B, DPP3

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  20532389

• Physical Properties:

  Liquid