DPP6 Antibody

• Background:

  This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  1804

• Swiss Prot:

  P42658

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 117-210 of human DPP6 (NP_001277182.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 105kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:2000

• Symbol:

  DPP6

• NCBI Official Name:

  Dipeptidyl peptidase like 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DPL1, DPPX, MRD33, VF2, dipeptidyl aminopeptidase-like protein 6, DPP VI, dipeptidyl aminopeptidase IV-related protein, dipeptidyl peptidase IV-related protein, dipeptidyl peptidase VI, dipeptidyl-peptidase 6

• Tested Applications:

  WB

• Physical Properties:

  Liquid