IRF2 Antibody

• Background :

  IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq].

• NCBI Gene ID :

  3660

• Swiss Prot :

  P14316

• Accession Number :

  P14316

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This IRF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from the Central region of human IRF2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  39 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  IRF2

• NCBI Official Name :

  Interferon regulatory factor 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Lace, M.J., et al. Virology 399 (2) :270-279 (2010)

• Background Reference 03 :

  Masumi, A., et al. Biochem. Biophys. Res. Commun. 391 (4) :1623-1628 (2010)

• Background Reference 04 :

  Daley, D., et al. Hum. Genet. 125 (4) :445-459 (2009)

• Other Product Names :

  Interferon regulatory factor 2, IRF-2, IRF2

• Tested Applications :

  WB

• Protein ID :

  20141499

• Physical Properties :

  Liquid