IRF2 Antibody

• Background:

  IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq].

• NCBI Gene ID:

  3660

• Swiss Prot:

  P14316

• Accession Number:

  P14316

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This IRF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from the Central region of human IRF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  IRF2

• NCBI Official Name:

  Interferon regulatory factor 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Lace, M.J., et al. Virology 399 (2) :270-279 (2010)

• Background Reference 03:

  Masumi, A., et al. Biochem. Biophys. Res. Commun. 391 (4) :1623-1628 (2010)

• Background Reference 04:

  Daley, D., et al. Hum. Genet. 125 (4) :445-459 (2009)

• Other Product Names:

  Interferon regulatory factor 2, IRF-2, IRF2

• Tested Applications:

  WB

• Protein ID:

  20141499

• Physical Properties:

  Liquid