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IRF8 Antibody

CAT: 0223-31-203Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-203Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interferon consensus sequence-binding protein (Ion ChannelSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
NCBI Gene ID
3394
Swiss Prot
Q02556
Accession Number
NP_002154
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Zebrafish
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRF8 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
IRF8 antibody can be used for detection of IRF8 by ELISA at 1:62500. IRF8 antibody can be used for detection of IRF8 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IRF8
NCBI Official Name
Interferon regulatory factor 8
NCBI Organism
Homo sapiens
Background Reference 01
Kebin Liu, et al., (2007) Cancer Res 67:3301.
Other Product Names
IRF8, ICSBP, IRF-8, ICSBP1, H-ICSBP
Tested Applications
ELISA, WB, IHC
Protein ID
4504567
Physical Properties
Liquid

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