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THEMIS Antibody

CAT: 0223-55-693Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-693Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
387357
Swiss Prot
Q8N1K5
Accession Number
Q8N1K5
Host
Rabbit
Reactivity
Mouse
Immunogen
This THEMIS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-588 amino acids from the C-terminal region of human THEMIS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Symbol
THEMIS
NCBI Official Name
Protein THEMIS
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)
Background Reference 03
Bhatti, P., et al. Radiat. Res. 173 (2) :214-224 (2010)
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS, C6orf190, C6orf207
Tested Applications
WB, IHC-P
Protein ID
150421530
Physical Properties
Liquid

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