PHF12 Antibody

• Background:

  Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

• NCBI Gene ID:

  57649

• Swiss Prot:

  Q96QT6

• Accession Number:

  Q96QT6

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This PHF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-859 amino acids from the C-terminal region of human PHF12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  110 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PHF12

• NCBI Official Name:

  PHD finger protein 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (14) :5391-5396 (2006)

• Background Reference 02:

  Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (14) :5391-5396 (2006)

• Background Reference 03:

  Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)

• Background Reference 04:

  Yochum, G.S., et al. Mol. Cell. Biol. 22 (22) :7868-7876 (2002)

• Other Product Names:

  HGNC:20816

• Tested Applications:

  WB, IHC-P

• Protein ID:

  71153050

• Physical Properties:

  Liquid