IRF1 Antibody

CAT: 0223-55-641Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-641Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
NCBI Gene ID
3659
Swiss Prot
P10914
Accession Number
P10914
Host
Rabbit
Reactivity
Human
Immunogen
This IRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-286 amino acids from the C-terminal region of human IRF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other, Inflammasomes
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IRF1
NCBI Official Name
Interferon regulatory factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Silva, L.K., et al. Eur. J. Hum. Genet. 18 (11) :1221-1227 (2010)
Background Reference 02
Matsuzaki, S., et al. J. Immunol. 185 (8) :4863-4872 (2010)
Background Reference 03
Antonios, D., et al. J. Immunol. 185 (1) :89-98 (2010)
Background Reference 04
Lou, Y.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27 (3) :255-258 (2010)
Other Product Names
Interferon regulatory factor 1, IRF-1, IRF1
Tested Applications
WB
Protein ID
20178295
Physical Properties
Liquid

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