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CAF-1 Antibody

CAT: 0223-55-638Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-638Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
NCBI Gene ID
29883
Swiss Prot
Q9UIV1
Accession Number
Q9UIV1
Host
Rabbit
Reactivity
Human
Immunogen
This CAF-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human CAF-1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Mouse, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
CNOT7
NCBI Official Name
CCR4-NOT transcription complex subunit 7
NCBI Organism
Homo sapiens
Background Reference 01
Lau, N.C., et al. Biochem. J. 422 (3) :443-453 (2009)
Background Reference 02
Aslam, A., et al. Mol. Biol. Cell 20 (17) :3840-3850 (2009)
Background Reference 03
Miyasaka, T., et al. Cancer Sci. 99 (4) :755-761 (2008)
Background Reference 04
Nishida, K., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 63 (PT 12), 1061-1063 (2007) :
Other Product Names
CCR4-NOT transcription complex subunit 7, BTG1-binding factor 1, CCR4-associated factor 1, CAF-1, Caf1a, CNOT7, CAF1
Tested Applications
WB, IHC-P, IF
Protein ID
41713629
Physical Properties
Liquid