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BMP-4 Antibody [3H2]

CAT: 0223-38-231Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0223-38-231Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
NCBI Gene ID
652
Swiss Prot
P12644
Accession Number
P12644
Host
Mouse
Reactivity
Human
Immunogen
BMP-4 antibody is produced in mice using highly pure (>98%) recombinant human BMP-4 as the immunizing antigen.
Clonality
Monoclonal
Clone
3H2
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies, Antibody Pairs
Field of Research
Signal Transduction
Purification
This IgG2bK antibody was purified from cell culture by Protein G affinity chromatography.
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
BMP-4 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.
Symbol
BMP4
NCBI Official Name
Bone morphogenetic protein 4
NCBI Organism
Homo sapiens
Other Product Names
Bone morphogenetic protein, BMP2B, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4, ZYME, OFC11, BMP2B1, MCOPS6
Tested Applications
ELISA, WB, Neutralization Assay
Protein ID
115073
Physical Properties
Lyophilized

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Alternative Products

CatalogName
AM26107PU-NLaminin alpha 4 (LAMA4) Mouse Monoclonal Antibody [Clone ID: 3H2]
sc-12721BMP-4 (3H2.3)
sc-12721 PEBMP-4 (3H2.3) PE
sc-12721 HRPBMP-4 (3H2.3) HRP
sc-12721 ACBMP-4 (3H2.3) AC
sc-12721 FITCBMP-4 (3H2.3) FITC
sc-12721 AF594BMP-4 (3H2.3) Alexa Fluor® 594
sc-12721 AF488BMP-4 (3H2.3) Alexa Fluor® 488
sc-12721 AF647BMP-4 (3H2.3) Alexa Fluor® 647
sc-12721 AF680BMP-4 (3H2.3) Alexa Fluor® 680

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