BMP-4 Antibody [3H2]

• Background:

  BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

• NCBI Gene ID:

  652

• Swiss Prot:

  P12644

• Accession Number:

  P12644

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  BMP-4 antibody is produced in mice using highly pure (>98%) recombinant human BMP-4 as the immunizing antigen.

• Clonality:

  Monoclonal

• Clone:

  3H2

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research:

  Signal Transduction

• Purification:

  This IgG2bK antibody was purified from cell culture by Protein G affinity chromatography.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  BMP-4 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.

• Symbol:

  BMP4

• NCBI Official Name:

  Bone morphogenetic protein 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Bone morphogenetic protein, BMP2B, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4, ZYME, OFC11, BMP2B1, MCOPS6

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  115073

• Physical Properties:

  Lyophilized