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ST2 Antibody

CAT: 0223-36-261Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-36-261Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
NCBI Gene ID
9173
Swiss Prot
Q01638
Accession Number
116242527
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human soluble ST2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Concentration
1 mg/ml
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Specificity
Recognizes soluble human ST2. Detects a band of ~50kDa by Western blot.
Applications Notes
ELISA: (direct and indirect: 1:2,000-1:5,000) . Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature) . Optimal conditions must be determined individually for each application.
Symbol
IL1RL1
NCBI Official Name
Interleukin 1 receptor like 1
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; IL-33 Receptor; Interleukin-33 Receptor
Tested Applications
ELISA, WB
Protein ID
Q01638
Physical Properties
Liquid

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