CCNB1 Antibody

• Background:

  The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

• NCBI Gene ID:

  891

• Swiss Prot:

  P14635

• Accession Number:

  P14635

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CCNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-268 amino acids from the Central region of human CCNB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat, Zebrafish, Hamster, B

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CCNB1

• NCBI Official Name:

  G2/mitotic-specific cyclin-B1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kreis, N.N., et al. Oncogene 29 (41) :5591-5603 (2010)

• Background Reference 02:

  Van Zon, W., et al. J. Cell Biol. 190 (4) :587-602 (2010)

• Background Reference 03:

  Harley, M.E., et al. EMBO J. 29 (14) :2407-2420 (2010)

• Background Reference 04:

  Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

• Other Product Names:

  G2/mitotic-specific cyclin-B1, CCNB1, CCNB

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116176

• Physical Properties:

  Liquid