RORA Antibody

CAT: 0223-55-471Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-471Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.
NCBI Gene ID
6095
Swiss Prot
P35398
Accession Number
P35398
Host
Rabbit
Reactivity
Human
Immunogen
This RORA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from human RORA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Symbol
RORA
NCBI Official Name
Nuclear receptor ROR-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Lechtken, A., Biochem. Biophys. Res. Commun. 358 (3), 890-896 (2007)
Background Reference 02
Lanoix, D., Hum. Reprod. 21 (8), 1981-1989 (2006)
Background Reference 03
Boukhtouche, F., J. Neurochem. 96 (6), 1778-1789 (2006)
Background Reference 04
Klar, J., Eur. J. Hum. Genet. 13 (8), 928-934 (2005)
Other Product Names
Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, RORA, NR1F1, RZRA
Tested Applications
WB, IF
Protein ID
548814
Physical Properties
Liquid

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