RORA Antibody

• Background:

  RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.

• NCBI Gene ID:

  6095

• Swiss Prot:

  P35398

• Accession Number:

  P35398

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RORA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from human RORA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RORA

• NCBI Official Name:

  Nuclear receptor ROR-alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lechtken, A., Biochem. Biophys. Res. Commun. 358 (3), 890-896 (2007)

• Background Reference 02:

  Lanoix, D., Hum. Reprod. 21 (8), 1981-1989 (2006)

• Background Reference 03:

  Boukhtouche, F., J. Neurochem. 96 (6), 1778-1789 (2006)

• Background Reference 04:

  Klar, J., Eur. J. Hum. Genet. 13 (8), 928-934 (2005)

• Other Product Names:

  Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, RORA, NR1F1, RZRA

• Tested Applications:

  WB, IF

• Protein ID:

  548814

• Physical Properties:

  Liquid