HNRNPC Antibody

• Background:

  This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].

• NCBI Gene ID:

  3183

• Swiss Prot:

  P07910

• Accession Number:

  P07910

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rabbit

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HNRNPC

• NCBI Official Name:

  Heterogeneous nuclear ribonucleoproteins C1/C2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Konig, J., et al. Nat. Struct. Mol. Biol. 17 (7) :909-915 (2010)

• Background Reference 02:

  Lee, E.K., et al. Nat. Struct. Mol. Biol. 17 (6) :732-739 (2010)

• Background Reference 03:

  Brunner, J.E., et al. Virology 400 (2) :240-247 (2010)

• Background Reference 04:

  Ertel, K.J., et al. J. Virol. 84 (9) :4229-4242 (2010)

• Other Product Names:

  Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC

• Tested Applications:

  WB, IHC-P

• Protein ID:

  108935845

• Physical Properties:

  Liquid