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HNRNPC Antibody

CAT: 0223-55-373Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-373Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq].
NCBI Gene ID
3183
Swiss Prot
P07910
Accession Number
P07910
Host
Rabbit
Reactivity
Human
Immunogen
This HNRNPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the C-terminal region of human HNRNPC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Symbol
HNRNPC
NCBI Official Name
Heterogeneous nuclear ribonucleoproteins C1/C2
NCBI Organism
Homo sapiens
Background Reference 01
Konig, J., et al. Nat. Struct. Mol. Biol. 17 (7) :909-915 (2010)
Background Reference 02
Lee, E.K., et al. Nat. Struct. Mol. Biol. 17 (6) :732-739 (2010)
Background Reference 03
Brunner, J.E., et al. Virology 400 (2) :240-247 (2010)
Background Reference 04
Ertel, K.J., et al. J. Virol. 84 (9) :4229-4242 (2010)
Other Product Names
Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC
Tested Applications
WB, IHC-P
Protein ID
108935845
Physical Properties
Liquid

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