SORBS1 Antibody

• Background:

  Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity) .

• NCBI Gene ID:

  10580

• Swiss Prot:

  Q9BX66

• Accession Number:

  Q9BX66

• Host:

  Rabbit

• Reactivity:

  Human, Hamster

• Immunogen:

  This SORBS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 866-892 amino acids from the Central region of human SORBS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  143 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SORBS1

• NCBI Official Name:

  Sorbin and SH3 domain-containing protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010) Gehmlich, K., et al. Eur. J. Cell Biol. 89 (5) :351-364 (2010) Yamada, Y., et al. Hypertens. Res. 32 (5) :325-331 (2009) Fernow, I., et al. BMC Cell Biol. 10, 80 (2009) :

• Other Product Names:

  HGNC:14565

• Tested Applications:

  WB, IF

• Protein ID:

  317373504

• Physical Properties:

  Liquid