Products for Research Use Only
RegisterLogin

IL12_2 Antibody

CAT: 0223-55-341Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-55-341Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
NCBI Gene ID
3595
Swiss Prot
Q99665
Accession Number
Q99665
Host
Rabbit
Reactivity
Human
Immunogen
This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
97 kDa
Fragment
Rabbit Ig
Symbol
IL12RB2
NCBI Official Name
Interleukin-12 receptor subunit beta-2
NCBI Organism
Homo sapiens
Background Reference 01
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Liu, X., et al. Nat. Genet. 42 (8) :658-660 (2010)
Background Reference 04
Mizuki, N., et al. Nat. Genet. 42 (8) :703-706 (2010)
Other Product Names
Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2
Tested Applications
WB, IHC-P, Flow
Protein ID
12229836
Physical Properties
Liquid

Related Products

CatalogName
55-192IL12B Antibody
42-608IL1R2 Antibody
45-767IL12B Antibody
55-587IL1R2 Antibody
18-370IL1R2 Antibody
60-064Mouse Il12b Antibody
45-766Il12 beta Antibody
45-767PIL12B Peptide
42-608PIL1R2 Peptide
10-193Ustekinumab (IL12B) - Research Grade Biosimilar

Alternative Products

CatalogName
E10G34310IL12_2 Rabbit Polyclonal Antibody
E45R03464G-4IL12_2 Antibody (C-term)
GTR18979502IL12_2 Antibody Blocking peptide
APR03464G-01IL12_2 Antibody (C-term) [APR03464G]
MBS9217787-01IL12_2 Antibody (C-term) Blocking peptide
E2618341IL12_2 (C-term) Rabbit pAb
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody

Popular Products