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SELPLG Antibody

CAT: 0223-55-196Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-196Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.
NCBI Gene ID
6404
Swiss Prot
Q14242
Accession Number
Q14242
Host
Rabbit
Reactivity
Human
Immunogen
This SELPLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-405 amino acids from the C-terminal region of human SELPLG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
SELPLG
NCBI Official Name
P-selectin glycoprotein ligand 1
NCBI Organism
Homo sapiens
Background Reference 01
Elmas, E., et al. J. Cardiovasc. Electrophysiol. 21 (11) :1260-1265 (2010)
Background Reference 02
Luan, S.L., et al. J. Pathol. 222 (2) :166-179 (2010)
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Russo, H.M., et al. Circ. Res. 107 (3) :388-397 (2010)
Other Product Names
P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG
Tested Applications
WB, Flow
Protein ID
2498904
Physical Properties
Liquid

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