SELPLG Antibody

• Background:

  SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters.

• NCBI Gene ID:

  6404

• Swiss Prot:

  Q14242

• Accession Number:

  Q14242

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SELPLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-405 amino acids from the C-terminal region of human SELPLG.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SELPLG

• NCBI Official Name:

  P-selectin glycoprotein ligand 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Elmas, E., et al. J. Cardiovasc. Electrophysiol. 21 (11) :1260-1265 (2010)

• Background Reference 02:

  Luan, S.L., et al. J. Pathol. 222 (2) :166-179 (2010)

• Background Reference 03:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 04:

  Russo, H.M., et al. Circ. Res. 107 (3) :388-397 (2010)

• Other Product Names:

  P-selectin glycoprotein ligand 1, PSGL-1, Selectin P ligand, CD162, SELPLG

• Tested Applications:

  WB, Flow

• Protein ID:

  2498904

• Physical Properties:

  Liquid