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ANGPT1 Antibody

CAT: 0223-55-185Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-185Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
NCBI Gene ID
284
Swiss Prot
Q15389
Accession Number
Q15389
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
ANGPT1
NCBI Official Name
Angiopoietin-1
NCBI Organism
Homo sapiens
Background Reference 01
Fang, X., et al. J. Biol. Chem. 285 (34) :26211-26222 (2010)
Background Reference 02
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 03
Choe, J.Y., et al. Joint Bone Spine 77 (4) :340-344 (2010)
Background Reference 04
Roberts, K.E., et al. Gastroenterology 139 (1) :130-139 (2010)
Other Product Names
Angiopoietin-1, ANG-1, ANGPT1, KIAA0003
Tested Applications
WB
Protein ID
12229574
Physical Properties
Liquid

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