Fibronectin Antibody [SPM246]

• Background:

  Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This mAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this mAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating mAb indicating that it can be used to specifically target tumor vessels in vivo.

• NCBI Gene ID:

  2335

• Swiss Prot:

  P02751

• Host:

  Mouse

• Reactivity:

  Human, Pig, Mouse, Rat

• Immunogen:

  A T-lymphoma biopsy was used as the immunogen for this Fibronectin antibody.

• Clonality:

  Monoclonal

• Clone:

  SPM246

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Applications Notes:

  1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.

• Symbol:

  FN1

• NCBI Official Name:

  Fibronectin 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  FN1, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, FINC, FN, LETS, MSF, FNZ, ED-B, GFND, GFND2

• Tested Applications:

  Flow, IF, IHC

• Physical Properties:

  Liquid