Growth Hormone Antibody [GRHP1-1]

• Background:

  Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly) .

• NCBI Gene ID:

  2688

• Swiss Prot:

  X07896

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A human partial recombinant protein was used as the immunogen for this Growth Hormone antibody.

• Clonality:

  Monoclonal

• Clone:

  GRHP1-1

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction, Cancer, Neuroscience

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2b

• Applications Notes:

  1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.

• Symbol:

  Growth Hormone

• NCBI Official Name:

  Dictyoglomus thermophilum amylase gene

• NCBI Organism:

  Dictyoglomus thermophilum

• Other Product Names:

  GH1, Growth hormone, GH, GHN, IGHD1B, GH-N, Pituitary growth hormone, Growth hormone 1, HGH-N, Somatotropin

• Tested Applications:

  Flow, IHC, IF

• Physical Properties:

  Liquid