Growth Hormone Antibody [GH/1450]

• Background:

  Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly) .

• NCBI Gene ID:

  2688

• Swiss Prot:

  P01241

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A human partial recombinant protein corresponding to amino acids 58-187 was used as the immunogen for this GH antibody.

• Clonality:

  Monoclonal

• Clone:

  GH/1450

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction, Cancer, Neuroscience

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2b

• Symbol:

  Growth Hormone

• NCBI Official Name:

  Growth hormone 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GH1, Growth hormone, GH, GHN, IGHD1B, GH-N, Pituitary growth hormone, Growth hormone 1, HGH-N, Somatotropin

• Tested Applications:

  WB, Flow, IHC-P, IF

• Physical Properties:

  Liquid