Neuron Specific Enolase Antibody [SPM347]

• Background:

  Recognizes a protein of about 50kDa, which is identified as gamma-Enolase/Neuron Specific Enolase/Enolase 2. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue and gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.

• NCBI Gene ID:

  2026

• Swiss Prot:

  P09104

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 416-433 of human Neuron Specific Enolase were used as the immunogen for this NSE antibody.

• Clonality:

  Monoclonal

• Clone:

  SPM347

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Stem Cell

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2b

• Symbol:

  ENO2

• NCBI Official Name:

  Enolase 2 (gamma, neuronal)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ENO2, Enolase 2, Enolase 2 (gamma, neuronal), Neurone-specific enolase, Gamma-enolase, Neural enolase, Neuron specific gamma enolase, Neuron-specific enolase, NSE

• Tested Applications:

  WB, IHC, Flow, IF

• Physical Properties:

  Liquid