Products for Research Use Only

TIMP2 Antibody [SPM356]

CAT: 0223-33-734Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-734Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2) . It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A) . It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B) . TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
NCBI Gene ID
7077
Swiss Prot
P16035
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.
Clonality
Monoclonal
Clone
SPM356
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2a, kappa
Symbol
TIMP2
NCBI Official Name
TIMP metallopeptidase inhibitor 2
NCBI Organism
Homo sapiens
Other Product Names
TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K
Tested Applications
IHC-P, IF, WB
Physical Properties
Liquid