Desmoglein 3 Antibody [5H10]

• Background:

  Recognizes a protein of 130kDa, identified as Desmoglein-3 (DSG3) . This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members are identified and all are members of the cadherin cell adhesion molecule superfamily.

• NCBI Gene ID:

  1830

• Swiss Prot:

  P32926

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A recombinant human protein corresponding to the extracellular portion of DSG3 was used as the immunogen for the Desmoglein 3 antibody.

• Clonality:

  Monoclonal

• Clone:

  5H10

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  DSG3

• NCBI Official Name:

  Desmoglein 3

• NCBI Organism:

  Homo sapiens

• Tested Applications:

  WB, Flow, IF, IP

• Physical Properties:

  Liquid