CD49e Antibody [5H10.27]

• Background:

  The monoclonal antibody 5H10.27 reacts with the alpha5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.

• NCBI Gene ID:

  16402

• Swiss Prot:

  P11688

• Accession Number:

  P11688

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  C57BL/6 x A/J F1 mouse mast cell line MC/9

• Clonality:

  Monoclonal

• Clone:

  [5H10.27]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in PBS

• Modification:

  None

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store vial at -20˚ C

• Fragment:

  IgG2a

• Specificity:

  CD49e

• Applications Notes:

  CD49e Antibody [5H10.27] for use in flow cytometry, immunohistochemistry, costimulation, blocking, and adhesion assays.

• Symbol:

  Itga5

• NCBI Official Name:

  Integrin alpha 5 (fibronectin receptor alpha)

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Integrin alpha5, VLA-5alpha

• Tested Applications:

  Flow

• Physical Properties:

  Liquid