CD27 Antibody [203.6]

• Background:

  Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028) . CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

• NCBI Gene ID:

  939

• Swiss Prot:

  P26842

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Sezary cells were used as the immunogen for the CD27 antibody.

• Clonality:

  Monoclonal

• Clone:

  203.6

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG3, kappa

• Symbol:

  CD27

• NCBI Official Name:

  CD27 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7

• Tested Applications:

  Flow, IF

• Physical Properties:

  Liquid