CD2 Antibody [HuLy-m1]

• Background:

  CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

• NCBI Gene ID:

  914

• Swiss Prot:

  P06729

• Host:

  Mouse

• Reactivity:

  Human, Cat

• Immunogen:

  Human thymocytes were used as the immunogen for the CD2 antibody.

• Clonality:

  Monoclonal

• Clone:

  HuLy-m1

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2b, kappa

• Symbol:

  CD2

• NCBI Official Name:

  CD2 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CD2, CD2 antigen, Erythrocyte receptor, LFA-3 receptor, LFA-2, Lymphocyte-function antigen-2, T11, SRBC, CD2 molecule, Rosette receptor, T-cell surface antigen CD2

• Tested Applications:

  Functional Assays, Flow, IF, WB

• Physical Properties:

  Liquid