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CD3 Antibody [B-B12]

CAT: 0223-33-274Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-274Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.
NCBI Gene ID
916
Swiss Prot
P07766
Host
Mouse
Reactivity
Human
Immunogen
Human T cell leukemia cells were used as immunogen for the CD3 antibody.
Clonality
Monoclonal
Clone
B-B12
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
CD3E
NCBI Official Name
CD3e molecule, epsilon (CD3-TCR complex)
NCBI Organism
Homo sapiens
Other Product Names
T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E
Tested Applications
WB, Flow, IF
Physical Properties
Liquid

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