HSP60 Antibody [LK2]

• Background:

  This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60) . The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp’s), more appropriately called as stress response proteins (srp’s) . HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.

• NCBI Gene ID:

  3329

• Swiss Prot:

  P10809

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Hamster, Guinea pig, Monkey, Chicken, E. coli, Borellia, Bacteria, Helminths, Yeast

• Immunogen:

  Recombinant human HSP60 protein was used as the immunogen for this antibody.

• Clonality:

  Monoclonal

• Clone:

  LK2

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  HSPD1

• NCBI Official Name:

  Heat shock 60kDa protein 1 (chaperonin)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, HSPD1, HSP60

• Tested Applications:

  WB, Flow, IF

• Physical Properties:

  Liquid