HSP70 Antibody

• Background:

  This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

• NCBI Gene ID:

  3303

• Swiss Prot:

  P0DMV8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 540 to the C-terminus of human HSP70 (NP_005336.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 72kDa

• Fragment:

  IgG

• Symbol:

  HSPA1A

• Positive Control 2:

  NIH/3T3

• Positive Control 3:

  COS-1

• Positive Control 4:

  COS-7

• Positive Control 5:

  U2OS

• Positive Control 6:

  293T

• NCBI Official Name:

  Heat shock 70kDa protein 1A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HSPA1A, HSP72, HSPA1, HSP70I, HSP70-1, HSP70-1A, HEL-S-103

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid