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CD47 Antibody [B6H12.2]

CAT: 0223-33-099Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-099Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
NCBI Gene ID
961
Swiss Prot
Q08722
Host
Mouse
Reactivity
Human
Immunogen
Intact CD47 purified from placenta was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
B6H12.2
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
CD47
NCBI Official Name
CD47 molecule
NCBI Organism
Homo sapiens
Other Product Names
Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, IAP, Protein MER6, CD47, CD47, MER6
Tested Applications
WB, Flow, IF, Blocking, IHC
Physical Properties
Liquid

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