PACS-1 Antibody

• Background:

  PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor) . PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.

• NCBI Gene ID:

  55690

• Swiss Prot:

  Q6VY07

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A recombinant protein fragment from the intermal portion of human PACS-1 was used as the immunogen for this antibody.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Homeostasis, Infectious Disease, Stem Cell

• Purification:

  Protein A affinity chromatography

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG

• Symbol:

  PACS1

• NCBI Official Name:

  Phosphofurin acidic cluster sorting protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Phosphofurin acidic cluster sorting protein 1, PACS-1, MRD17

• Tested Applications:

  WB

• Physical Properties:

  Liquid