SLC5A12 Antibody

• Background:

  Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na (+) -coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na (+) -coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]) .

• NCBI Gene ID:

  159963

• Swiss Prot:

  Q1EHB4

• Accession Number:

  Q1EHB4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SLC5A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-605 amino acids from the C-terminal region of human SLC5A12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  68 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SLC5A12

• NCBI Official Name:

  Sodium-coupled monocarboxylate transporter 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Gopal, E., et al. Biochim. Biophys. Acta 1768 (11) :2690-2697 (2007)

• Other Product Names:

  Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12, SLC5A12, SMCT2

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  189046187

• Physical Properties:

  Liquid