RBBP9 Antibody

• Background:

  RBBP9 may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.

• NCBI Gene ID:

  10741

• Swiss Prot:

  O75884

• Accession Number:

  NP_006597

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RBBP9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1208 - THP-1 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RBBP9 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  21 kDa

• Applications Notes:

  RBBP9 antibody can be used for detection of RBBP9 by ELISA at 1:1562500. RBBP9 antibody can be used for detection of RBBP9 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  RBBP9

• NCBI Official Name:

  Retinoblastoma binding protein 9

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, J., (2003) J. Hum. Genet. 48 (4), 164-169 .

• Other Product Names:

  RBBP9, BOG, MGC9236, RBBP10

• Tested Applications:

  ELISA, WB

• Protein ID:

  24119166

• Physical Properties:

  Liquid