CLDN18 Antibody

CAT: 0223-31-269Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-31-269Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]) .
NCBI Gene ID
51208
Swiss Prot
P56856
Accession Number
NP_057453
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN18.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLDN18 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa
Applications Notes
CLDN18 antibody can be used for detection of CLDN18 by ELISA at 1:62500. CLDN18 antibody can be used for detection of CLDN18 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CLDN18
NCBI Official Name
Claudin 18
NCBI Organism
Homo sapiens
Background Reference 01
Karanjawala, Z.E., (2008) Am. J. Surg. Pathol. 32 (2), 188-196 .
Other Product Names
CLDN18, SFTA5, SFTPJ
Tested Applications
ELISA, WB
Protein ID
7705961
Physical Properties
Liquid

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