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CLDN19 Antibody

CAT: 0223-18-842Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-18-842Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO) . HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
NCBI Gene ID
149461
Swiss Prot
Q8N6F1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-80 of human CLDN19 (NP_001116867.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CLDN19
Positive Control 2
Mouse kidney
NCBI Official Name
Claudin 19
NCBI Organism
Homo sapiens
Other Product Names
HOMG5, claudin-19
Tested Applications
WB
Physical Properties
Liquid

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