POU3F2 Antibody

CAT: 0223-31-205Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-31-205Size:100 µL
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Background
N-Oct-3 (POU3F2) is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1) and Oct2 (POU2F2), and the pituitary protein Pit1 (PIT1) . Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression. N-Oct-3 is a protein belonging to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, which occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176), and the pituitary protein Pit1 (PIT1; MIM 173110) . Class III POU genes are expressed predominantly in the CNS. It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression.[supplied by OMIM].
NCBI Gene ID
5454
Swiss Prot
P20265
Accession Number
NP_005595
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human POU3F2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Tranfected 293T Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store POU3F2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
47 kDa
Applications Notes
POU3F2 antibody can be used for detection of POU3F2 by ELISA at 1:62500. POU3F2 antibody can be used for detection of POU3F2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
POU3F2
NCBI Official Name
POU class 3 homeobox 2
NCBI Organism
Homo sapiens
Background Reference 01
Goodall, J., (2004) Mol. Cell. Biol. 24 (7), 2923-2931.
Other Product Names
POU3F2, BRN2, OCT7, OTF7, OTF-7, POUF3, brn-2, oct-7, N-Oct3
Tested Applications
ELISA, WB
Protein ID
51702521
Physical Properties
Liquid

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