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HTR3A Antibody

CAT: 0223-31-116Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-116Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
NCBI Gene ID
3359
Swiss Prot
P46098
Accession Number
NP_000860
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTR3A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
55 kDa
Applications Notes
HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HTR3A
NCBI Official Name
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
NCBI Organism
Homo sapiens
Background Reference 01
Panicker, S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158.
Other Product Names
HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
Tested Applications
ELISA, WB, IHC
Protein ID
253735700
Physical Properties
Liquid

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