HTR2A Antibody

• Background:

  HTR2A belongs to the G-protein coupled receptor 1 family. It is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

• NCBI Gene ID:

  3356

• Swiss Prot:

  P28223

• Accession Number:

  NP_000612

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR2A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTR2A antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Applications Notes:

  HTR2A antibody can be used for detection of HTR2A by ELISA at 1:312500. HTR2A antibody can be used for detection of HTR2A by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  HTR2A

• NCBI Official Name:

  5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yoon, H.K. (er) Prog. Neuropsychopharmacol. Biol. Psychiatry (2008) In press.

• Other Product Names:

  HTR2A, 5-HT2A, HTR2

• Tested Applications:

  ELISA, WB

• Protein ID:

  10835175

• Physical Properties:

  Liquid