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CCL18 Antibody

CAT: 0223-31-060Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-060Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
NCBI Gene ID
6362
Swiss Prot
P55774
Accession Number
NP_002979
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCL18.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCL18 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
10 kDa
Applications Notes
CCL18 antibody can be used for detection of CCL18 by ELISA at 1:62500. CCL18 antibody can be used for detection of CCL18 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CCL18
NCBI Official Name
Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
NCBI Organism
Homo sapiens
Background Reference 01
Schraufstatter, I., et al., (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 286 (3), L494-L501.
Other Product Names
CCL18, CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18
Tested Applications
ELISA, WB, IHC
Protein ID
4506831
Physical Properties
Liquid

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