CCL18 Antibody

• Background:

  CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.

• NCBI Gene ID:

  6362

• Swiss Prot:

  P55774

• Accession Number:

  NP_002979

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCL18.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction, Immunology

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCL18 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  10 kDa

• Applications Notes:

  CCL18 antibody can be used for detection of CCL18 by ELISA at 1:62500. CCL18 antibody can be used for detection of CCL18 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CCL18

• NCBI Official Name:

  Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Schraufstatter, I., et al., (2004) Am. J. Physiol. Lung Cell Mol. Physiol. 286 (3), L494-L501.

• Other Product Names:

  CCL18, CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  4506831

• Physical Properties:

  Liquid