BCL2 Antibody

• Background:

  The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.

• NCBI Gene ID:

  596

• Swiss Prot:

  P10415

• Accession Number:

  NP_000624

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Cell Cycle, Cancer, Signal Transduction, Immunology

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1309 - Human Placenta Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BCL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  26 kDa

• Applications Notes:

  BCL2 antibody can be used for detection of BCL2 by ELISA at 1:312500. BCL2 antibody can be used for detection of BCL2 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BCL2

• NCBI Official Name:

  B-cell CLL/lymphoma 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, R., et al., (2004) J. Cell Biol. 166 (2), 193-203.

• Other Product Names:

  BCL2, Bcl-2, PPP1R50

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  72198189

• Physical Properties:

  Liquid